Category: Lifestyle

Excessive calcium contributes to harmful inflammation in ischemic stroke, and targeting it may provide doctors with a new way to improve patient outcomes, new research from the University of Virginia School of Medicine suggests. Petr Tvrdik, Ph.D., has found that immune cells called microglia are flooded with waves of calcium in the wake of ischemic […]

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects. Preclinical studies found the small-molecule enolase inhibitor to be effective in killing brain cancer cells that were missing ENO1, one of two genes encoding the […]

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active “super immune cells” with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center. The reprogramming involves a novel approach the researchers developed that inhibits the activity of proteins known as MEK1/2. Currently, several […]

Many children are willing to make personal sacrifices to punish wrongdoers—and even more so if they believe punishment will teach the transgressor a lesson, a new Yale study published Nov. 23 in the journal Nature Human Behaviour shows. Philosophers and psychologists have long argued whether the main reason people punish others for bad behavior is […]

Severe infections like malaria cause short and long-term damage to precursor blood cells in mice, but some damage could be reversed, find researchers. A team led by researchers from Imperial College London and The Francis Crick Institute have discovered that severe infections caused by malaria disrupt the processes that form blood cells in mice. This […]

Physicians and scientists at Cincinnati Children’s Hospital Medical Center used new stem cell technology to regenerate and study living patient-specific skin in the lab, giving them a precise close up view of how inherited DNA defects cause skin damage and deadly squamous cell carcinoma in children and young adults with Fanconi anemia (FA). Reporting their […]

Amusement and pleasant surprises—and the laughter they can trigger—add texture to the fabric of daily life. Those giggles and guffaws can seem like just silly throwaways. But laughter, in response to funny events, actually takes a lot of work, because it activates many areas of the brain: areas that control motor, emotional, cognitive and social […]